Doxycycline - Doxycycline Hyclate 100 mg: What you need to know prior buying

Doxycycline Hyclate 100mg is the generic name (with the standard dosage mentioned) for the medication and it’s pronounced DOX-i-Cy (as in cyber)-kleen HYE-klate. Vibramycin and other Vibra-Tabs fall under the doxycycline medications. Other dosages of doxycycline available are 40 mg, 50mg and 75 mg; as a suspension of 25 mg/teaspoon; a Syrup of 50 mg/teaspoon and in a powder form for injecting in strengths of 42.5 mg, 100mg and 200 mg. Doxycycline needs being preserved at a room temperature (15°C -30°C or 59°F -86°F) away from light. However, the powder demands a temperature of 25°C (77°F) or lower maintained with the rest of the conditions fulfilled.

This antibiotic treats a broad spectrum of bacterial infections in both humans and animals. It is particularly effective against Hemophilus influenzae, Mycoplasma pneumoniae, Streptococcus pneumoniae, Chlamydia psittaci, Neisseria gonorrhoea and Chlamydia trachomatis. However, it is combinations that work out better for acne and certain infections caused by amoeba. This tetracycline antibiotic slows bacterial growth stopping their internal protein synthesis and helps the body’s immune system to take over on bacteria. This particular mechanism of action makes doxycycline a potent antidote against malaria, tick-fever (both in humans and animals) and anthrax, if administered immediately after initial exposure. Doxycycline is particularly effective in slowing the progression and sometimes, even prevents it.

There’s no dietary restriction to be followed while on Doxycycline but a big ‘BUT’ remains associated with doxycycline hyclate uses for those allergic to the tetracycline group itself or on acitretin, penicillin or isotretinoin medications. Besides, a live typhoid vaccine (oral) taken is also a strict ‘no’ to doxycycline. The same is advised to pregnant or breastfeeding ladies; to be on the safe-side, stay away from doxycycline for at least 30 days if you are planning to conceive, for Doxycycline interferes with the genes forming the teeth and bones. Doxycycline passes into the fetus (or into an infant through breast milk) and may bring about malformation of teeth and/or bones in growing children. It is generally a good idea to be on external probiotic (beneficial bacterium found in the intestinal tract of healthy mammals) source with doxycycline for it doesn’t discriminate between the necessary and unnecessary and may give rise to diarrhea otherwise. And those with ulcerative skin diseases or with porphyria (a metabolic disorder that’s genetic) must double check before you pop one at will.

Other relatively harmless doxycycline hyclate side effects are interactions occurring with barbiturates, diuretics and/or urinary alkalinizers and the compound chelates readily with calcium and iron. In both cases, the compound is not allowed to act upon the body; hence, the effectiveness of Doxycycline Hyclate is lost.

List of medications that might trigger serious doxycycline hyclate side effects:

• Acitretin and anticoagulants: Acitretin gives rise to benign intracranial hypertension (increased blood pressure in the brain) when taken with doxycycline while increases the effects of anticoagulants by several folds by increasing plasma levels, sometimes resulting in severe bleeding.
• Carbamazepine, Digoxin and isotretinoin: Carbamazepine is a potent enzyme inducer with powers to increase doxycycline metabolism and decreasing the body’s serum concentrations, which together decreases the medication’s antibacterial efficacy; while with digoxin, doxycycline disrupts the calcium levels and nullifies digoxin’s power to set right irregular heart beat. Isotretinoin, when taken with any of the tetracyclines increases greatly the chances for idiopathic intracranial hypertension.
• Methotrexate and methoxyflurane: Gives rise to an impaired/abnormal liver function, hepatic necrosis, failure and encephalopathy.
• Hormonal birth control measures and diuretics: Both reduce the efficiency of the medication.
• Penicillin medications: Doxycycline hyclate will disrupt the beneficial effects of penicillin and shall slow down the healing of the symptom being treated by penicillin.